Huntington's Disease

[HuntWarrior]

Dear all,

It is a long time a go that there was a specific project for our disease.

Ofcourse we keep folding as much as possible.

I learned there is a protein called HAPP32, any chance this will be investigated?

Is it fair to assume, that the nowadays projects will benifit HD aswell ?

If possible, I would like to have some "proof" to stimulate HD folders in the Netherlands evenmore.

Looking forward to replies.

Best Regards

Hans van der Leer (Team 46113)

[VijayPande]

We have strong interest in HD (right behind our primary efforts in Alzheimer's Disease). It turns out that there are enough similarities between AD and HD that we can share methodology from AD to HD. We have 2 papers on HD which we're working on to submit soon (i.e. within the next few months) for peer review.

[science man]

Dear all,

It is a long time a go that there was a specific project for our disease.

Ofcourse we keep folding as much as possible.

I learned there is a protein called HAPP32, any chance this will be investigated?

Is it fair to assume, that the nowadays projects will benifit HD aswell ?

If possible, I would like to have some "proof" to stimulate HD folders in the Netherlands evenmore.

Looking forward to replies.

Best Regards

Hans van der Leer (Team 46113)

HuntWarriar relax. I'm sure fah is working on cures for all diseases and cancers know to man like VijaryPande said I quote

We have strong interest in HD (right behind our primary efforts in Alzheimer's Disease). It turns out that there are enough similarities between AD and HD that we can share methodology from AD to HD. We have 2 papers on HD which we're working on to submit soon (i.e. within the next few months) for peer review.

So just keep running your client.

[alancabler]

So much to learn, so little processing power... build another rig and get your friends on board!

[HuntWarrior]

Vijay please read,

So much to learn, so little processing power... build another rig and get your friends on board!

Our families are dedicated allright, our team consisted of 117 members, who die to hear something possitive out of folding in general but specificly for HD ofcourse.
At the moment only 17 teammenber are actively folding, that brought us to team position 856 out of almost 14000, not to bad.
It is not only about demotivation because of lack of info, we are motivated allright but the bit of stimulating news I gave them after starting this topic needs follow up.
They are wondering if i was telling tales........or what is going on.
I know it all takes time for a cure, but info gives hope aswell.
Beside all that, HD families usualy are more short of cash than average, so they want to invest their little money in something they can believe in.
Please read back the topic from post 1.

I invested allright Alancabler: Q6600, HD 4870 at 3.6GHZ

If my cashflow was good enough, there would be more!

The electricitybill for 24/7 folding is hard enough to afford for me, not being able to work.

Happy with the increase the GPU client gives to almost 3PFLP

Hope it all pay's off one day (will stay dedicated for life or as long as neccessary)

[Rapt0r]

Vijay please read,

So much to learn, so little processing power... build another rig and get your friends on board!

Our families are dedicated allright, our team consisted of 117 members, who die to hear something possitive out of folding in general but specificly for HD ofcourse.
At the moment only 17 teammenber are actively folding, that brought us to team position 856 out of almost 14000, not to bad.
It is not only about demotivation because of lack of info, we are motivated allright but the bit of stimulating news I gave them after starting this topic needs follow up.
They are wondering if i was telling tales........or what is going on.
I know it all takes time for a cure, but info gives hope aswell.
Beside all that, HD families usualy are more short of cash than average, so they want to invest their little money in something they can believe in.
Please read back the topic from post 1.

I invested allright Alancabler: Q6600, HD 4870 at 3.6GHZ

If my cashflow was good enough, there would be more!

The electricitybill for 24/7 folding is hard enough to afford for me, not being able to work.

Happy with the increase the GPU client gives to almost 3TFLP

Hope it all pay's off one day (will stay dedicated for life or as long as neccessary)

I am a fan of AMD, but the Client-Core for Nvidia-GPU's is getting more work done at this time.
If you bougth your rig only for folding you missed to buy the right Hardware.
And ff you have a empty pcie x16 slot left right now you can bye a GT 256 or 512 MB for a little money to gain ~5000 ppd more.

But he is generaly right, we need more active folders. So much are inactive! Maybe they don't have the money to pay their electricity-bill?

[HuntWarrior]

More or less Offtopic

Hi Rapt0r,

My Rigg is a year old and modified here and there, folding for about 3 years 24/7.

Thanks for your tip, scoring points is important .

MORE POINTS IS INDEED MORE SCIENCE!

More projectinfo, gives more motivation to the inactive folders!!

More science info,more info whats being done with results and by whom and so on.

Preferrably in not to much "scienced language" ......

AMD/ATI will come with more suitable drivers to continue the folding "battle"

I thought Nvidia uses a little more watts/money ?

[Rapt0r]

More or less Offtopic

Hi Rapt0r,

My Rigg is a year old and modified here and there, folding for about 3 years 24/7.

Thanks for your tip, scoring points is important .

MORE POINTS IS INDEED MORE SCIENCE!

More projectinfo, gives more motivation to the inactive folders!!

More science info,more info whats being done with results and by whom and so on.

Preferrably in not to much "scienced language" ......

AMD/ATI will come with more suitable drivers to continue the folding "battle"

I thought Nvidia uses a little more watts/money ?

So that's easy to say.
I think AMD/ATI in their current financial state, isn't at the position to push the resources for a evoling development in GPU2 ATI Client.
Folding@home isn't so much important as Endusermarket-Sells. The Drivers for Streamcompution like AMD called this, is so unimportant at the moment you cannot even visualize.
1,189 milliard euros loss. Intel has more win as amd loss. So believe me, they don't waste any breath for folding in such a hard time like now.

[HuntWarrior]

Sorry Rapt0r,

The intention of this story was information=motivation.

[Rapt0r]

Sorry Rapt0r,

The intention of this story was information=motivation.

I agree.

[HuntWarrior]

I am translating the main and rest of the website info in Dutch at the moment, so hopefully we'll get a gain in Dutch folders in general and maybe for our team: 46113 ?

[Kakao]

HuntWarrior congratulations. Don't worry if you can't buy and support more hardware. I think you are contributing more translating the site than if you were to build a small farm. Keeping updated to support your team is also great contribution.

[nwkelley]

Hi HuntWarrior,
yes as vijay has mentioned we have a paper out for review right now actually, some work i had done with xuhui and some experimental collaborators, and there will shortly be a second paper submitted. I will make a forum post when it is due to be published! (as you know it can be a length process however
-nick

PS what was it specifically that you had recently read concerning HAPP32?

[HuntWarrior]

Hi kakao,

Thanks for the compliments, you are right the team spirit is nice but it is the qualtity and science delivered what counts!

Hi Nick,

I learned about Happ32 from some of your guys (Dell Lucent??) on the former forum, would appreciate it very much to hear, when the papers are finished.
It would be a good way to stimulate Dutch HD families to fold even more.
To my idea it is the Huntington's Accosiated Protein also know as Huntingtin ??? (HT) am I right ?

Hans

[DaveHand]

Looking forward to some good news on this disease too.

But until then, I will be very happy to read (and try to understand) the results of any related FAH projects.


Thanks.