Protein vibrations?

[P5-133XL]

I just read http://www.sciencedaily.com/releases/20 ... 084838.htm. It would seem to me that such vibrations would significantly affect folding. Further that different folding shapes could produce different resonant frequencies that may be characteristic and testable. Also a simulator, like F@H, that uses atomic forces would be a good way to predict such interactions.

[bruce]

Science question:

I don't suppose that anybody has looked at the spectrum of a protein in vitro and compared it to the spectrum in silico?
Just how good are our models?

[VijayPande]

This is a pretty new technique. It's hard for me to tell how useful it will be, but it's definitely interesting. And new types of experiments can be very powerful additions to the weapons we can bring to bear on a problem.