Folding Forum

I'm curious as to why you think any pharmaceutical company will 'let this rot on the vine'. They do exist to generate novel therapeutics and sell them. The pande lab has a long standing interest in small molecule inhibitors of protein-protein interaction. There is a large difference in the discovery...

Hi, We actually have 2 current research projects in the areas you mention. We have had a project on new compounds to inhibit Abeta aggregation (these compounds are designed to mimic regions of abeta identified from Abeta aggregation simulations running on folding@home). In addition we have been deve...

With all drug screening its important to have a counter screen to determine if the result you see is a 'false positive'. I.e its having an effect in your assay, but possibly for the wrong reasons, such as interfering with the functional readout etc, or in this case binding non specifically to the pr...